Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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4,351 – 4,365 of 5,522 results

4,351

eMolecules Ambeed (4-Formyl-phenyl)-carbamicacidtert-butylester 250mg 521412715 A164452 0 000 144072-30-0 MFCD06245541 221 256 C12H15NO3

Ambeed (4-Formyl-phenyl)-carbamicacidtert-butylester 250mg 521412715 A164452 0 000 144072-30-0 MFCD06245541 221 256 C12H15NO3

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4,352

eMolecules 16959-62-9 | methyl indolizine-2-carboxylate | Pharmablock | MFCD13178636 | 175.187 | C10H9NO2 | 97.000 | COC(=O)c1cc2ccccn2c1 | 50mg | 788527013

methyl indolizine-2-carboxylate | Pharmablock | 16959-62-9 | MFCD13178636 | 175.187 | C10H9NO2 | 97.000 | COC(=O)c1cc2ccccn2c1 | 50mg | 788527013

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4,353

Medchemexpress LLC Lodoxamide (U-42585E free acid) | 53882-12-5 | 98.1% | C11H6ClN3O6 | 200 MG

Lodoxamide (U-42585E free acid) is an antiallergic compound that acts as a mast-cell stabilizer, used for the treatment of asthma and allergic conjunctivitis.

Inhibits histamine release and calcium influx in mast cells.
Reduces chemotactic response of eosinophils to fMLP and IL-5.
Inhibits eosinophil peroxidase release after IgA-dependent activation.
Demonstrates cromolyn-like activity in mast cell assays and antigen-sensitized rhesus monkeys.
Inhibits increased respiratory frequency and decreased tidal volume induced by antigen challenge.
Reduces lung reperfusion injury in organ preservation solutions.
Improves daytime breathing difficulty, cough, sputum, and sleep in patients.

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4,354

eMolecules 939-16-2 | 3-Bromo-2-quinolinol | Combi-Blocks | MFCD00234482 | 224.057 | C9H6BrNO | 96.000 | Oc1nc2ccccc2cc1Br | 1g | 457920314

3-Bromo-2-quinolinol | Combi-Blocks | 939-16-2 | MFCD00234482 | 224.057 | C9H6BrNO | 96.000 | Oc1nc2ccccc2cc1Br | 1g | 457920314

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4,355

Medchemexpress LLC B7-H2/ICOSLG protein, cynomolgus | >95.0% | 20 UG

B7-H2/ICOSLG protein (cynomolgus) is a recombinant extracellular domain of the ICOS ligand produced in HEK293 mammalian cells with a C-terminal His tag. Supplied lyophilized from PBS (pH 7.4), the protein is intended for immunology and receptor-ligand interaction studies and is characterized by low endotoxin and a defined amino acid range (M1-T256).

Recombinant protein expressed in HEK293 mammalian cells.
C-terminal His tag for purification and detection.
Amino acid range M1-T256 corresponding to the extracellular domain.
Observed molecular weight 50-70 kDa.
Endotoxin <1 EU/μg (LAL method).
Lyophilized formulation from PBS, pH 7.4; recommend aliquoting for storage.

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4,356

Apexbio Technology LLC Tubastatin A 1252003-15-8 200mg

Tubastatin A (CAS 1252003-15-8) is a selective inhibitor of histone deacetylase 6 (HDAC6) an enzyme mediating acetylation states crucial for regulating both histone and non-histone proteins Tubastatin A inhibits HDAC6 with an IC50 of approximately 15 nM and shows minimal activity against class I HDAC isoforms demonstrating greater than 200-fold selectivity In vitro Tubastatin A induces hyperacetylation of -tubulin reduces neuronal cell death inhibits inflammatory cytokines (IL-6 TNF) production in human THP-1 macrophages and decreases NO secretion from mouse Raw 264 7 cells In animal models it exhibits anti-inflammatory and anti-tumor effects Tubastatin A is utilized in research exploring cancer biology inflammation and neuroprotection

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4,357

eMolecules 118-13-8 | 3-Hydroxyquinoline-4-carboxylic acid | Apollo Scientific | MFCD01536959 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1c(O)cnc2ccccc12 | 1g | 562430305

3-Hydroxyquinoline-4-carboxylic acid | Apollo Scientific | 118-13-8 | MFCD01536959 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1c(O)cnc2ccccc12 | 1g | 562430305

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4,358

Apexbio Technology LLC Clinofibrate 30299-08-2 200mg

Clinofibrate (CAS 30299-08-2) is a small-molecule lipid-regulating agent that modulates cholesterol and triglyceride metabolism It acts by inhibiting hydroxymethylglutaryl coenzyme A reductase (HMGCR) a key enzyme in the biosynthetic pathway of cholesterol Clinofibrate demonstrates an inhibitory concentration (IC50) of 0 47 mM against HMGCR indicating its potential to suppress cholesterol synthesis It is primarily utilized in biomedical research focused on the regulation of plasma lipid levels and the investigation of therapeutic strategies for hypercholesterolemia and hypertriglyceridemia

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4,359

Medchemexpress LLC Snx-2112 | 908112-43-6 | 99.5% | 464.48 g/mol | C23H27F3N4O3 | 200 MG

SNX-2112 is an Hsp90 inhibitor research compound used to study Hsp90-mediated signaling and cancer cell biology. It binds Hsp90 isoforms with low-nanomolar affinity and induces degradation of client proteins, making it suitable for biochemical and cellular assays.

High purity (99.5%) appropriate for sensitive assays.
Molecular weight 464.48 g/mol.
White to off-white solid, easy to weigh and dissolve.
Stable when stored as a powder at -20°C for long-term storage.
Supplied in a 200 MG quantity for laboratory use.

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4,360

eMolecules 74668-72-7 | 2-Methoxy-8-quinolinol | MFCD00168952 | 1g

Combi-Blocks, Inc. | 2-Methoxy-8-quinolinol | 1g | 603147589 | QK-4186 | 95.000 | 74668-72-7 | MFCD00168952 | 175.187 | C10H9NO2

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4,361

TARGETMOL CHEMICALS INC OROTIRELIN 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Orotirelin(CG 3509) a thyrotropin-releasing hormone analog reversed pentobarbital-induced sleep time.Orotirelin may be beneficial in animals with focal cerebral ischemia. purity: 100%

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4,362

Apexbio Technology LLC AS 602801 848344-36-5 200mg

AS 602801 (CAS 848344-36-5) is a selective small-molecule inhibitor targeting c-Jun N-terminal kinase (JNK) a kinase implicated in immune and apoptotic signaling pathways Preclinical studies indicate that AS 602801 suppresses T-cell proliferation and promotes apoptosis altering gene expression in RRMS-derived CD4 and CD8 T-cells and innate receptor expression in RRMS-associated CD11b cells Animal models show beneficial effects in autoimmune disorders and neuronal apoptosis scenarios Thus AS 602801 is investigated primarily for therapeutic potential in multiple sclerosis and fibrotic conditions

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4,363

Medchemexpress LLC Succinimidyl 3-(2-pyridyldithio)propionate | 68181-17-9 | MFCD00009636 | 99.1% | 312.37 g/mol | C12H12N2O4S2 | 200 MG

Succinimidyl 3-(2-pyridyldithio)propionate (SPDP) is a heterobifunctional, cleavable crosslinker that links primary amines to sulfhydryl groups via an NHS ester and a pyridyldithiol moiety, forming a reducible disulfide bond useful for reversible bioconjugation and antibody-drug conjugates.

Short spacer arm for minimal linker length.
Reacts with primary amines via an NHS ester.
Couples to sulfhydryls through a pyridyldithiol group.
Forms a glutathione-cleavable disulfide bond.
Suitable for reversible protein conjugation and ADC linker strategies.
High purity and defined molecular weight for reproducible results.

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4,364

Apexbio Technology LLC TAK-438 1260141-27-2 200mg

TAK-438 is a small-molecule inhibitor targeting gastric H K -ATPase It is designed to reversibly block potassium-competitive activity of this enzyme thereby suppressing gastric acid secretion TAK-438 exerts its biological activity primarily through direct potassium-competitive inhibition of the gastric H K -ATPase enzyme In animal studies TAK-438 demonstrates concentration-dependent inhibition of histamine-stimulated acid secretion in rats and dogs with effects persisting beyond 24 hours after oral administration Based on these pharmacological properties TAK-438 holds research potential in studies involving gastric acid physiology and acid-related gastrointestinal disorders

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4,365

TARGETMOL CHEMICALS INC YKL-06-061 10MG

Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3 respectively. purity: 99%

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Quinolines and derivatives

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Medchemexpress LLC Lodoxamide (U-42585E free acid) | 53882-12-5 | 98.1% | C11H6ClN3O6 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC B7-H2/ICOSLG protein, cynomolgus | >95.0% | 20 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Snx-2112 | 908112-43-6 | 99.5% | 464.48 g/mol | C23H27F3N4O3 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Succinimidyl 3-(2-pyridyldithio)propionate | 68181-17-9 | MFCD00009636 | 99.1% | 312.37 g/mol | C12H12N2O4S2 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Lodoxamide (U-42585E free acid) | 53882-12-5 | 98.1% | C11H6ClN3O6 | 200 MG

Medchemexpress LLC B7-H2/ICOSLG protein, cynomolgus | >95.0% | 20 UG

Medchemexpress LLC Snx-2112 | 908112-43-6 | 99.5% | 464.48 g/mol | C23H27F3N4O3 | 200 MG

Medchemexpress LLC Succinimidyl 3-(2-pyridyldithio)propionate | 68181-17-9 | MFCD00009636 | 99.1% | 312.37 g/mol | C12H12N2O4S2 | 200 MG