Quinolines and derivatives
Medchemexpress LLC Afalanine (N-Acetyl-DL-phenylalanine) | 2901-75-9 | 99.9% | 200 MG
Afalanine (N-Acetyl-DL-phenylalanine) is an endogenous metabolite of an endophytic fungus with antidepressant activity. It can be used in combination with antibiotics to prevent renal damage.
- Endogenous metabolite of an endophytic fungus
- Antidepressant activity
- Can be used in combination with antibiotics to prevent renal damage
- For research use only
Medchemexpress LLC Tenatoprazole | 113712-98-4 | 99.8% | 346.40 | 200 MG
Tenatoprazole (TU-199) is an orally active imidazopyridine-based proton pump inhibitor characterized by a prolonged plasma half-life. It inhibits hog gastric H+/K+-ATPase activity and blocks the interaction of ubiquitin with the ESCRT-1 factor Tsg101.
- Orally active imidazopyridine-based proton pump inhibitor.
- Characterized by a prolonged plasma half-life.
- Inhibits hog gastric H+/K+-ATPase activity.
- Blocks the interaction of ubiquitin with the ESCRT-1 factor Tsg101.
- Inhibits the production of several enveloped viruses, including EBV.
Medchemexpress LLC Hispidol ((Z)-hispidol) | 5786-54-9 | 98.3% | 254.24 g·mol⁻¹ | C15H10O4 | 200 MG
Hispidol ((Z)-Hispidol) is a small-molecule TNF-α inhibitor used in research applications. It inhibits TNF-α-induced adhesion of monocytes to colon epithelial cells (IC50 = 0.50 μM) and is supplied as a solid analytical standard (CAS 5786-54-9).
- Inhibits TNF-α-induced adhesion of monocytes to colon epithelial cells (IC50 = 0.50 μM).
- Chemical formula C15H10O4.
- Molecular weight 254.24 g·mol⁻¹.
- Purity 98.3% (manufacturer listed).
- Appearance solid, light yellow to yellow.
- Suitable for research and analytical applications.
- Storage: powder -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC (-)-Huperzine A | 102518-79-6 | 99.7% | 242.32 | 200 MG
(-)-Huperzine A | 102518-79-6 | 99.7% | 242.32 | 200 MG
![eMolecules 898747-24-5 | 5-Bromo-1H-indazole-7-carboxylic acid methyl ester | J & W PharmLab LLC | MFCD08458991 | 255.071 | C9H7BrN2O2 | 96.000 | COC(=O)c1cc(Br)cc2cn[nH]c12 | 5g | 289352063](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000225216.jpg-250.jpg)
eMolecules 898747-24-5 | 5-Bromo-1H-indazole-7-carboxylic acid methyl ester | J & W PharmLab LLC | MFCD08458991 | 255.071 | C9H7BrN2O2 | 96.000 | COC(=O)c1cc(Br)cc2cn[nH]c12 | 5g | 289352063
5-Bromo-1H-indazole-7-carboxylic acid methyl ester | J & W PharmLab LLC | 898747-24-5 | MFCD08458991 | 255.071 | C9H7BrN2O2 | 96.000 | COC(=O)c1cc(Br)cc2cn[nH]c12 | 5g | 289352063
Medchemexpress LLC Amino-PEG3-C2-sulfonic acid | 1817735-43-5 | 99.5% | 257.30 | 50 MG
Amino-PEG3-C2-sulfonic acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules containing two ligands connected by a linker: one for an E3 ubiquitin ligase and another for the target protein. Their application involves exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Applicable in cancer and cancer targeted therapy
Medchemexpress LLC B7-H2/ICOSLG Mouse 5ug
B7-H2/ICOSLG is an important ligand of the T cell receptor ICOS and mediates immune responses It acts as a costimulatory signal promoting T and B cell proliferation cytokine secretion and plasma cell differentiation B7-H2/ICOSLG Protein Mouse (HEK293 His) is the recombinant mouse-derived B7-H2/ICOSLG protein expressed by HEK293 with C-His labeled tag
eMolecules 303085-53-2 | 6-Chloropyridazine-3-carbaldehyde | Combi-Blocks, Inc. | MFCD10698041 | 142.540 | C5H3ClN2O | 98.000 | Clc1ccc(C=O)nn1 | 10g | 603143868
6-Chloropyridazine-3-carbaldehyde | Combi-Blocks, Inc. | 303085-53-2 | MFCD10698041 | 142.540 | C5H3ClN2O | 98.000 | Clc1ccc(C=O)nn1 | 10g | 603143868
TARGETMOL CHEMICALS INC L-Sodium lactate 200MG
Also available in 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. (L)-Sodium lactate (Sodium L-Lactate) is produced from pyruvate by the enzyme Lactate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells. L-Lactic Acid occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and other organs and body fluids. Purity 99.17%
Apexbio Technology LLC LDK378 1032900-25-6 200mg
LDK378 (CAS 1032900-25-6) is a potent inhibitor of anaplastic lymphoma kinase (ALK) a receptor tyrosine kinase within the insulin receptor superfamily It exhibits an in vitro IC50 of 200 pM for ALK and displays moderate to high inhibitory activity against a limited set of other kinases including IGF-1R (IC50 8 nM) InsR (IC50 7 nM) and STK22D (IC50 23 nM) LDK378 suppresses proliferation of Ba/F3 cells transfected with NPM-ALK fusion and Karpas 299 human lymphoma cells harboring NPM-ALK with IC50 values of 22 8 nM and 26 nM respectively The compound is widely used in preclinical studies to investigate ALK-driven signaling and its potential as a therapeutic target in oncology
Medchemexpress LLC Sugammadex sodium | 343306-79-6 | 98.0% | C72H104Na8O48S8 | 200 MG
Sugammadex sodium is a synthetic γ-cyclodextrin derivative that acts as a reversal agent for neuromuscular block. It also shows a nephroprotective effect in ischemia-reperfusion injury.
- Acts as a reversal agent for neuromuscular block.
- Exhibits nephroprotective effects in ischemia-reperfusion injury.
Medchemexpress LLC DC-BPi-03 | 2758411-46-8 | C14H14N4O2S | 200 MG
DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC50 of 698.3 nM and a Kd of 2.81 μM. This compound is intended for research use only.
- Potent BPTF-BRD inhibitor
- IC50 of 698.3 nM
- Kd of 2.81 μM
- Purity of 99.77%
- White to off-white solid appearance
Apexbio Technology LLC PCI-24781 (CRA-024781) 783355-60-2 200mg
PCI-24781 (CRA-024781 CAS 783355-60-2) is a histone deacetylase (HDAC) inhibitor targeting HDAC1 HDAC2 HDAC3 HDAC6 HDAC8 and HDAC10 with reported Ki values of 7 19 8 2 17 280 and 24 nM respectively HDAC enzymes catalyze the removal of acetyl groups from lysine residues on histone proteins thereby regulating chromatin structure and gene expression PCI-24781 induces dose-dependent hyperacetylation of histones and tubulin in human cancer cells (HCT116 DLD-1) leading to apoptosis via p21 upregulation PARP cleavage and H2AX accumulation PCI-24781 demonstrates antitumor activity against multiple tumor cell lines and in xenograft models highlighting its utility for oncology research
Medchemexpress LLC Corticosterone | 50-22-6 | 99.8% | 200 MG
Corticosterone is an orally active glucocorticoid produced by the adrenal cortex. It is involved in regulating neuronal functions within the limbic system, including the hippocampus, prefrontal cortex, and amygdala.
- Enhances Rab-mediated AMPAR membrane traffic through SGK-induced phosphorylation of GDI.
- Has an immunosuppressive effect by interfering with dendritic cell maturation.
Apexbio Technology LLC Epalrestat 82159-09-9 200mg
Epalrestat (CAS 82159-09-9) is an orally available inhibitor of aldose reductase the rate-limiting enzyme of the polyol pathway involved in glucose metabolism By suppressing aldose reductase activity epalrestat limits intracellular sorbitol accumulation in neural tissues a process implicated in diabetic complications This compound is frequently employed in experimental models of diabetic neuropathy to investigate how modulation of the polyol pathway affects disease pathology and cellular signaling Epalrestat thus serves as a valuable molecular tool for elucidating the pathophysiology and pharmacology relevant to diabetes-associated neuronal damage